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Therefore, to ensure the safety and efficacy of allicin in preventing and treating CVD and to better understand its effects, it is imperative to conduct large-scale randomized clinical trials and further basic research

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Celastrol has also been effective against mesangioproliferative glomerulonephritis (Guo et al., 2017), recent studies (Chu et al., 2014) have additionally reported that Celastrol ameliorates IR-AKI, which correlates with inhibiting NF-B activation and inflammation